Cargando…

Loganin Prevents Hepatic Steatosis by Blocking NLRP3 Inflammasome Activation

Activation of the NLRP3 inflammasome is a necessary process to induce fibrosis in nonalcoholic fatty liver disease (NAFLD). Nonalcoholic steatohepatitis (NASH) is a kind of NAFLD that encompasses the spectrum of liver disease. It is characterized by inflammation and ballooning of hepatocytes during...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jang, Joo Hyeon, Yang, Gabsik, Seok, Jin Kyung, Kang, Han Chang, Cho, Yong-Yeon, Lee, Hye Suk, Lee, Joo Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810450/ https://www.ncbi.nlm.nih.gov/pubmed/36111592 http://dx.doi.org/10.4062/biomolther.2022.077

Ejemplares similares

Loganin Alleviates Gout Inflammation by Suppressing NLRP3 Inflammasome Activation and Mitochondrial Damage
por: Choi, Nuri, et al.
Publicado: (2021)

Sweroside Prevents Non-Alcoholic Steatohepatitis by Suppressing Activation of the NLRP3 Inflammasome
por: Yang, Gabsik, et al.
Publicado: (2020)

Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis
por: Lee, Hye Eun, et al.
Publicado: (2019)

Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells
por: Lee, Hye Eun, et al.
Publicado: (2019)

Repurposing Auranofin, an Anti-Rheumatic Gold Compound, to Treat Acne Vulgaris by Targeting the NLRP3 Inflammasome
por: Yang, Gabsik, et al.
Publicado: (2020)

Therapeutic regulation of the NLRP3 inflammasome in chronic inflammatory diseases
por: Seok, Jin Kyung, et al.
Publicado: (2021)

A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet
por: Yang, Gabsik, et al.
Publicado: (2016)

Regulation of the NLRP3 Inflammasome by Post-Translational Modifications and Small Molecules
por: Seok, Jin Kyung, et al.
Publicado: (2021)

Erratum: A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet
por: Yang, Gabsik, et al.
Publicado: (2016)

Inflammasomes and their roles in arthritic disease pathogenesis
por: Yang, Gabsik, et al.
Publicado: (2022)

Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation
por: Cheng, Yu-Chi, et al.
Publicado: (2020)

Targeting ASC in NLRP3 inflammasome by caffeic acid phenethyl ester: a novel strategy to treat acute gout
por: Lee, Hye Eun, et al.
Publicado: (2016)

Novel role of NLRP3-inflammasome in regulation of lipogenesis in fasting-induced hepatic steatosis
por: Liu, Baoqing, et al.
Publicado: (2019)

Melatonin ameliorates hepatic steatosis by inhibiting NLRP3 inflammasome in db/db mice
por: Yu, Yongxiang, et al.
Publicado: (2021)

A Novel Treatment Strategy by Natural Products in NLRP3 Inflammasome-Mediated Neuroinflammation in Alzheimer’s and Parkinson’s Disease
por: Lee, Jun Ho, et al.
Publicado: (2021)

Effects of Loganin on Bone Formation and Resorption In Vitro and In Vivo
por: Lee, Chang-Gun, et al.
Publicado: (2022)

Skin Barrier Abnormalities and Immune Dysfunction in Atopic Dermatitis
por: Yang, Gabsik, et al.
Publicado: (2020)

Natural Products as a Novel Therapeutic Strategy for NLRP3 Inflammasome-Mediated Gout
por: Lee, Jun Ho, et al.
Publicado: (2022)

Inhibitory Effects of Loganin on Adipogenesis In Vitro and In Vivo
por: Jeon, Hyoju, et al.
Publicado: (2023)

RIG-I Deficiency Promotes Obesity-Induced Insulin Resistance
por: Yang, Gabsik, et al.
Publicado: (2021)

Lobeglitazone inhibits LPS-induced NLRP3 inflammasome activation and inflammation in the liver
por: Seo, Hye-Young, et al.
Publicado: (2023)

Loganin Attenuates the Severity of Acute Kidney Injury Induced by Cisplatin through the Inhibition of ERK Activation in Mice
por: Kim, Dong-Uk, et al.
Publicado: (2021)

Involvement of HO-1 and Autophagy in the Protective Effect of Magnolol in Hepatic Steatosis-Induced NLRP3 Inflammasome Activation In Vivo and In Vitro
por: Kuo, Ni-Chun, et al.
Publicado: (2020)

Improvement Effect of Soyeom Pharmacopuncture on Gout via NLRP3 Inflammasome Regulation
por: Kim, Sung Wook, et al.
Publicado: (2022)

Oxidized Phospholipids in Tumor Microenvironment Stimulate Tumor Metastasis via Regulation of Autophagy
por: Seok, Jin Kyung, et al.
Publicado: (2021)

Effects of XIAP on high fat diet-induced hepatic steatosis: a mechanism involving NLRP3 inflammasome and oxidative stress
por: Zilu, Shi, et al.
Publicado: (2019)

Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis
por: Zhang, Lu, et al.
Publicado: (2023)

Blocking Smad2 signalling with loganin attenuates SW10 cell cycle arrest induced by TNF-α
por: Chao, Gao, et al.
Publicado: (2017)

Gemigliptin Attenuates Renal Fibrosis Through Down-Regulation of the NLRP3 Inflammasome
por: Seo, Jung Beom, et al.
Publicado: (2019)

Tendril extract of Cucurbita moschata suppresses NLRP3 inflammasome activation in murine macrophages and human trophoblast cells
por: Park, Ji-Yeon, et al.
Publicado: (2020)

Spirulina maxima extract prevents activation of the NLRP3 inflammasome by inhibiting ERK signaling
por: Chei, Sungwoo, et al.
Publicado: (2020)

MARCH5‐dependent NLRP3 ubiquitination is required for mitochondrial NLRP3‐NEK7 complex formation and NLRP3 inflammasome activation
por: Park, Yeon‐Ji, et al.
Publicado: (2023)

ATL I, Acts as a SIRT6 Activator to Alleviate Hepatic Steatosis in Mice via Suppression of NLRP3 Inflammasome Formation
por: Kong, Danli, et al.
Publicado: (2022)

Ethanol extract of Chrysanthemum zawadskii inhibits the NLRP3 inflammasome by suppressing ASC oligomerization in macrophages
por: Jang, Ah-Ra, et al.
Publicado: (2023)

Quantitative ultrasound radiofrequency data analysis for the assessment of hepatic steatosis using the controlled attenuation parameter as a reference standard
por: Jeon, Sun Kyung, et al.
Publicado: (2021)

Mitophagy: a balance regulator of NLRP3 inflammasome activation
por: Kim, Min-Ji, et al.
Publicado: (2016)

Curcuma phaeocaulis Inhibits NLRP3 Inflammasome in Macrophages and Ameliorates Nanoparticle-Induced Airway Inflammation in Mice
por: Nam, Yeon-Ju, et al.
Publicado: (2022)

Ameliorative Effects of Loganin on Arthritis in Chondrocytes and Destabilization of the Medial Meniscus-Induced Animal Model
por: Park, Eunkuk, et al.
Publicado: (2021)

TLR2 and the NLRP3 inflammasome mediate IL-1β production in Prevotella nigrescens-infected dendritic cells
por: Jang, Hye-Mi, et al.
Publicado: (2021)

Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome
por: Yang, Chul-Su, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tm15v9bkocc0iamtlkpoev6680