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ETV3 and ETV6 enable monocyte differentiation into dendritic cells by repressing macrophage fate commitment

In inflamed tissues, monocytes differentiate into macrophages (mo-Macs) or dendritic cells (mo-DCs). In chronic nonresolving inflammation, mo-DCs are major drivers of pathogenic events. Manipulating monocyte differentiation would therefore be an attractive therapeutic strategy. However, how the bala...

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Detalles Bibliográficos
Autores principales: Villar, Javiera, Cros, Adeline, De Juan, Alba, Alaoui, Lamine, Bonte, Pierre-Emmanuel, Lau, Colleen M., Tiniakou, Ioanna, Reizis, Boris, Segura, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810530/
https://www.ncbi.nlm.nih.gov/pubmed/36543959
http://dx.doi.org/10.1038/s41590-022-01374-0