Cargando…

CD8α+ dendritic cells potentiate antitumor and immune activities against murine ovarian cancers

Dendritic cell (DC)-based immunotherapies have been shown to be a potential treatment option for various cancers; however, the exact strategies in ovarian cancer remain unknown. Here, we report the effectiveness of mouse CD8α+ DCs derived from bone marrow hematopoietic stem cells (BM-HSCs), equivale...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Shin-Wha, Lee, Hyunah, Lee, Kyung-Won, Kim, Min-Je, Kang, Sung Wan, Lee, Young-Jae, Kim, HyunSoo, Kim, Yong-Man
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810613/ https://www.ncbi.nlm.nih.gov/pubmed/36596856 http://dx.doi.org/10.1038/s41598-022-27303-7

Ejemplares similares

Combination therapy of renal cell carcinoma or breast cancer patients with dendritic cell vaccine and IL-2: results from a phase I/II trial
por: Baek, Soyoung, et al.
Publicado: (2011)

CD8α+ dendritic cells dictate immune responses against murine AML
por: Kline, Douglas E, et al.
Publicado: (2013)

Host type I IFN signals are required for antitumor CD8(+) T cell responses through CD8α(+) dendritic cells
por: Fuertes, Mercedes B., et al.
Publicado: (2011)

Application of Immunoprofiling Using Multiplexed Immunofluorescence Staining Identifies the Prognosis of Patients with High-Grade Serous Ovarian Cancer
por: Lee, Shin-Wha, et al.
Publicado: (2021)

RORα Regulates Cholesterol Metabolism of CD8(+) T Cells for Anticancer Immunity
por: Lee, In Kyu, et al.
Publicado: (2020)

Immunotherapy of Malignant Melanoma with Tumor Lysate-Pulsed Autologous Monocyte-Derived Dendritic Cells
por: Kim, Dae Suk, et al.
Publicado: (2011)

Intra-osseous injection of donor mesenchymal stem cell (MSC) into the bone marrow in living donor kidney transplantation; a pilot study
por: Lee, Hyunah, et al.
Publicado: (2013)

The expression and function of toll-like receptors (TLRs) in ovarian cancer cell lines
por: Lee, Shin-Wha, et al.
Publicado: (2015)

Combined Treatment of Murine Fibrosarcoma with Chemotherapy (Paclitaxel), Radiotherapy, and Intratumoral Injection of Dendritic Cells
por: Byun, Ji-Won, et al.
Publicado: (2014)

Antitumor Effect of KML-B-Treated Dendritic Cells via Induction of Lymphocyte Activation
por: Kim, Jong-Jin, et al.
Publicado: (2017)

Dendritic Cell (DC) Vaccine in Mouse Lung Cancer Minimal Residual Model; Comparison of Monocyte-derived DC vs. Hematopoietic Stem Cell Derived-DC
por: Baek, Soyoung, et al.
Publicado: (2012)

A Murine CD8(+) T Cell Epitope Identified in the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein
por: Yang, Jihyun, et al.
Publicado: (2021)

Resveratrol exerts antitumor effects by downregulating CD8(+)CD122(+) Tregs in murine hepatocellular carcinoma
por: Zhang, Qunfang, et al.
Publicado: (2020)

A phase I/IIa study of adjuvant immunotherapy with tumour antigen-pulsed dendritic cells in patients with hepatocellular carcinoma
por: Lee, Jeong-Hoon, et al.
Publicado: (2015)

CD8α(+) and CD8α(−) Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo
por: Maldonado-López, Roberto, et al.
Publicado: (1999)

Combined Treatment of an Intratumoral Injection of Dendritic Cells and Systemic Chemotherapy (Paclitaxel) for Murine Fibrosarcoma
por: Choi, Gwang-Seong, et al.
Publicado: (2005)

Synergistic Antimyeloma Activity of Dendritic Cells and Pomalidomide in a Murine Myeloma Model
por: Vo, Manh-Cuong, et al.
Publicado: (2018)

CD44 Disruption Attenuates Murine Hepatic Ischemia/Reperfusion Injury
por: Kim, Min Sung, et al.
Publicado: (2011)

Comprehensive Transcriptomic Comparison between Porcine CD8(−) and CD8(+) Gamma Delta T Cells Revealed Distinct Immune Phenotype
por: Kim, Sangwook, et al.
Publicado: (2021)

Radiation improves antitumor effect of immune checkpoint inhibitor in murine hepatocellular carcinoma model
por: Kim, Kyoung-Jin, et al.
Publicado: (2017)

Multimodality Imaging of Bone Marrow–Derived Dendritic Cell Migration and Antitumor Immunity()
por: Ahn, Su-Bi, et al.
Publicado: (2017)

Colonic Metastasis Presenting as an Intraluminal Fungating Mass 8 Years After Surgery for Ovarian Cancer
por: Kim, Jeong Rye, et al.
Publicado: (2015)

Blood monocyte-derived CD169(+) macrophages contribute to antitumor immunity against glioblastoma
por: Kim, Hyun-Jin, et al.
Publicado: (2022)

A Preliminary X-ray Study of Murine Tnfaip8/Oxi-α
por: Lee, Daeun, et al.
Publicado: (2014)

Combination therapy with dendritic cells and lenalidomide is an effective approach to enhance antitumor immunity in a mouse colon cancer model
por: Vo, Manh-Cuong, et al.
Publicado: (2017)

Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity
por: Mosaheb, Mubeen M., et al.
Publicado: (2020)

Allogeneic dendritic cells induce potent antitumor immunity by activating KLRG1(+)CD8 T cells
por: Wang, Chao, et al.
Publicado: (2019)

Deletion of Akt1 Promotes Kidney Fibrosis in a Murine Model of Unilateral Ureteral Obstruction
por: Kim, Il Young, et al.
Publicado: (2020)

Antitumor effects and mechanisms of dendritic cells stimulated by sCD40L on ovarian cancer cells in vitro
por: Zhang, Zheng-mao, et al.
Publicado: (2013)

Protocol to analyze antitumor immunity of orthotopic injection and spontaneous murine high-grade glioma models using flow cytometry and single-cell RNA sequencing
por: Park, Jang Hyun, et al.
Publicado: (2022)

CD8α(2) CD11b(+) Dendritic Cells Present Exogenous Virus-like Particles to CD8(+) T Cells and Subsequently Express CD8α and CD205 Molecules
por: Morón, Gabriel, et al.
Publicado: (2002)

Immunotherapy Using Dendritic Cells against Multiple Myeloma: How to Improve?
por: Nguyen-Pham, Thanh-Nhan, et al.
Publicado: (2012)

Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model
por: Kim, Hyun-Ah, et al.
Publicado: (2023)

Deoxypodophyllotoxin Induces a Th1 Response and Enhances the Antitumor Efficacy of a Dendritic Cell-based Vaccine
por: Lee, Jun Sik, et al.
Publicado: (2011)

An Improved Prediction Model for Ovarian Cancer Using Urinary Biomarkers and a Novel Validation Strategy
por: Lee, Shin-Wha, et al.
Publicado: (2019)

Ahnak-knockout mice show susceptibility to Bartonella henselae infection because of CD4+ T cell inactivation and decreased cytokine secretion
por: Choi, Eun Wha, et al.
Publicado: (2019)

Monocyte-Derived Dendritic Cells Dictate the Memory Differentiation of CD8(+) T Cells During Acute Infection
por: Shin, Kwang-Soo, et al.
Publicado: (2019)

Prospective study of the efficacy and utility of TP53 mutations in circulating tumor DNA as a non-invasive biomarker of treatment response monitoring in patients with high-grade serous ovarian carcinoma
por: Kim, Yong-Man, et al.
Publicado: (2018)

B7-H3×4-1BB bispecific antibody augments antitumor immunity by enhancing terminally differentiated CD8(+) tumor-infiltrating lymphocytes
por: You, Gihoon, et al.
Publicado: (2021)

3D Visualization of Dynamic Cellular Reaction of Pulpal CD11c+ Dendritic Cells against Pulpitis in Whole Murine Tooth
por: Hong, Sujung, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_t21nckkk5crua942bk1f53n4ku