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Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation

Here we explored the role of interleukin-1β (IL-1β) repressor cytokine, IL-1 receptor antagonist (IL-1rn), in both healthy and abnormal hematopoiesis. Low IL-1RN is frequent in acute myeloid leukemia (AML) patients and represents a prognostic marker of reduced survival. Treatments with IL-1RN and th...

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Detalles Bibliográficos
Autores principales:	Villatoro, Alicia, Cuminetti, Vincent, Bernal, Aurora, Torroja, Carlos, Cossío, Itziar, Benguría, Alberto, Ferré, Marc, Konieczny, Joanna, Vázquez, Enrique, Rubio, Andrea, Utnes, Peter, Tello, Almudena, You, Xiaona, Fenton, Christopher G., Paulssen, Ruth H., Zhang, Jing, Sánchez-Cabo, Fátima, Dopazo, Ana, Vik, Anders, Anderssen, Endre, Hidalgo, Andrés, Arranz, Lorena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810723/ https://www.ncbi.nlm.nih.gov/pubmed/36596811 http://dx.doi.org/10.1038/s41467-022-35700-9

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