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Targeted treatment of refractory primitive neuroectodermal tumor arising from an immature teratoma with crizotinib leading to a sustained response

Here we present a case of metastatic PNET which arose from an immature teratoma that was refractory to standard Ewing sarcoma chemotherapy. This PNET was determined to have elevated levels of ALK protein via IHC. The patient was treated with crizotinib on a palliative basis with a sustained response...

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Detalles Bibliográficos
Autores principales: Snyder, Benjamin M., Lion, Alex H., Helvie, Amy E., Marshall, Mark S., Ferguson, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810838/
https://www.ncbi.nlm.nih.gov/pubmed/36619485
http://dx.doi.org/10.1002/ccr3.6779