Cargando…

β3 adrenergic agonism: A novel pathway which improves right ventricular‐pulmonary arterial hemodynamics in pulmonary arterial hypertension

Efficacy of therapies that target the downstream nitric oxide (NO) pathway in pulmonary arterial hypertension (PAH) depends on the bioavailability of NO. Reduced NO level in PAH is secondary to “uncoupling” of endothelial nitric oxide synthase (eNOS). Stimulation of β3 adrenergic receptors (β3 ARs)...

Descripción completa

Detalles Bibliográficos
Autores principales: Karimi Galougahi, Keyvan, Zhang, Yunjia, Kienzle, Vivian, Liu, Chia‐Chi, Quek, Lake‐Ee, Patel, Sanjay, Lau, Edmund, Cordina, Rachael L., Figtree, Gemma A., Celermajer, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810839/
https://www.ncbi.nlm.nih.gov/pubmed/36597221
http://dx.doi.org/10.14814/phy2.15549