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β3 adrenergic agonism: A novel pathway which improves right ventricular‐pulmonary arterial hemodynamics in pulmonary arterial hypertension
Efficacy of therapies that target the downstream nitric oxide (NO) pathway in pulmonary arterial hypertension (PAH) depends on the bioavailability of NO. Reduced NO level in PAH is secondary to “uncoupling” of endothelial nitric oxide synthase (eNOS). Stimulation of β3 adrenergic receptors (β3 ARs)...
Autores principales: | Karimi Galougahi, Keyvan, Zhang, Yunjia, Kienzle, Vivian, Liu, Chia‐Chi, Quek, Lake‐Ee, Patel, Sanjay, Lau, Edmund, Cordina, Rachael L., Figtree, Gemma A., Celermajer, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810839/ https://www.ncbi.nlm.nih.gov/pubmed/36597221 http://dx.doi.org/10.14814/phy2.15549 |
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