Childhood-onset systemic lupus erythematosus in the first year of life with joint involvement: A case report and mini-review

Systemic Lupus Erythematosus (SLE) is a multisystem disorder that can affect any organ system. It can have varied presentations, and often early disease is challenging to pick up due to the absence of classical features. Pediatric systemic lupus erythematosus is rare before five years of age. We report a seventeen-month-old female child who came to us with a long-standing non-specific febrile illness. She was eventually diagnosed with childhood-onset systemic lupus erythematosus and treated with prednisolone and hydroxychloroquine with vitamin D and calcium supplements.