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Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: An Italian single-institution 5-year experience analysis and updated literature review

BACKGROUND: Hemorrhoidal disease is a highly prevalent, chronic disorder that usually compromise patients' quality of life. Despite recent advances in pharmacologic and surgical therapeutic options, a clear treatment “gold standard” is lacking. Our aim is to analyze the outcomes following Trans...

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Autores principales: Verre, Luigi, Gallo, Gaetano, Grassi, Giulia, Bussolin, Edoardo, Carbone, Ludovico, Poto, Gianmario Edoardo, Carpineto Samorani, Osvaldo, Marano, Luigi, Marrelli, Daniele, Roviello, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811001/
https://www.ncbi.nlm.nih.gov/pubmed/36620384
http://dx.doi.org/10.3389/fsurg.2022.1088546
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author Verre, Luigi
Gallo, Gaetano
Grassi, Giulia
Bussolin, Edoardo
Carbone, Ludovico
Poto, Gianmario Edoardo
Carpineto Samorani, Osvaldo
Marano, Luigi
Marrelli, Daniele
Roviello, Franco
author_facet Verre, Luigi
Gallo, Gaetano
Grassi, Giulia
Bussolin, Edoardo
Carbone, Ludovico
Poto, Gianmario Edoardo
Carpineto Samorani, Osvaldo
Marano, Luigi
Marrelli, Daniele
Roviello, Franco
author_sort Verre, Luigi
collection PubMed
description BACKGROUND: Hemorrhoidal disease is a highly prevalent, chronic disorder that usually compromise patients' quality of life. Despite recent advances in pharmacologic and surgical therapeutic options, a clear treatment “gold standard” is lacking. Our aim is to analyze the outcomes following Transanal Hemorrhoidal Dearterialization (THD) procedure. METHODS: Patients who failed conservative treatment and underwent THD Doppler between 2017 and 2021 were enrolled. Follow-up interviews (consisting of clinical examination, Visual Analog Scale for pain—VAS, Vaizey incontinence score, Hemorrhoid Severity Score) were administered 1 week, 2 weeks, 1 month and 6 months after surgery. RESULTS: Forty-seven out of 75 patients were male, and the mean age was 50 (± 17.9) years. Hemorrhoids were classified as Goligher's degree II in 25 cases, III in 40 and IV, simple irreducible without ischemic changes, in 10. The mean operative time was 35 (28–60) minutes, and most procedures were performed with epidural anesthesia (80%). No intraoperative complications occurred, and 73 patients (97.3%) were discharged within post-operative day 1. Early post-operative pain and bleeding occurred in 37.3% and 8% of patients, respectively. No patients experienced anal incontinence and severe symptoms at 6 months after surgery. The overall success rate was 97.3%. CONCLUSIONS: THD is safe and effective in hemorrhoidal disease at degree II if bleeding, III, and IV without ischemic changes, both as a first intervention and on recurrence. Physician and patient need to understand each other's expectations, weight the risks and benefits, and customize the treatment.
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spelling pubmed-98110012023-01-05 Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: An Italian single-institution 5-year experience analysis and updated literature review Verre, Luigi Gallo, Gaetano Grassi, Giulia Bussolin, Edoardo Carbone, Ludovico Poto, Gianmario Edoardo Carpineto Samorani, Osvaldo Marano, Luigi Marrelli, Daniele Roviello, Franco Front Surg Surgery BACKGROUND: Hemorrhoidal disease is a highly prevalent, chronic disorder that usually compromise patients' quality of life. Despite recent advances in pharmacologic and surgical therapeutic options, a clear treatment “gold standard” is lacking. Our aim is to analyze the outcomes following Transanal Hemorrhoidal Dearterialization (THD) procedure. METHODS: Patients who failed conservative treatment and underwent THD Doppler between 2017 and 2021 were enrolled. Follow-up interviews (consisting of clinical examination, Visual Analog Scale for pain—VAS, Vaizey incontinence score, Hemorrhoid Severity Score) were administered 1 week, 2 weeks, 1 month and 6 months after surgery. RESULTS: Forty-seven out of 75 patients were male, and the mean age was 50 (± 17.9) years. Hemorrhoids were classified as Goligher's degree II in 25 cases, III in 40 and IV, simple irreducible without ischemic changes, in 10. The mean operative time was 35 (28–60) minutes, and most procedures were performed with epidural anesthesia (80%). No intraoperative complications occurred, and 73 patients (97.3%) were discharged within post-operative day 1. Early post-operative pain and bleeding occurred in 37.3% and 8% of patients, respectively. No patients experienced anal incontinence and severe symptoms at 6 months after surgery. The overall success rate was 97.3%. CONCLUSIONS: THD is safe and effective in hemorrhoidal disease at degree II if bleeding, III, and IV without ischemic changes, both as a first intervention and on recurrence. Physician and patient need to understand each other's expectations, weight the risks and benefits, and customize the treatment. Frontiers Media S.A. 2022-12-21 /pmc/articles/PMC9811001/ /pubmed/36620384 http://dx.doi.org/10.3389/fsurg.2022.1088546 Text en © 2022 Verre, Gallo, Grassi, Bussolin, Carbone, Poto, Carpineto Samorani, Marano, Marrelli and Roviello. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Verre, Luigi
Gallo, Gaetano
Grassi, Giulia
Bussolin, Edoardo
Carbone, Ludovico
Poto, Gianmario Edoardo
Carpineto Samorani, Osvaldo
Marano, Luigi
Marrelli, Daniele
Roviello, Franco
Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: An Italian single-institution 5-year experience analysis and updated literature review
title Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: An Italian single-institution 5-year experience analysis and updated literature review
title_full Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: An Italian single-institution 5-year experience analysis and updated literature review
title_fullStr Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: An Italian single-institution 5-year experience analysis and updated literature review
title_full_unstemmed Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: An Italian single-institution 5-year experience analysis and updated literature review
title_short Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: An Italian single-institution 5-year experience analysis and updated literature review
title_sort transanal hemorrhoidal dearterialization (thd) for hemorrhoidal disease: an italian single-institution 5-year experience analysis and updated literature review
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811001/
https://www.ncbi.nlm.nih.gov/pubmed/36620384
http://dx.doi.org/10.3389/fsurg.2022.1088546
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