Colorectal Cancer Metastases in the Liver Establish Immunosuppressive Spatial Networking between Tumor-Associated SPP1(+) Macrophages and Fibroblasts

PURPOSE: The liver is the most frequent metastatic site for colorectal cancer. Its microenvironment is modified to provide a niche that is conducive for colorectal cancer cell growth. This study focused on characterizing the cellular changes in the metastatic colorectal cancer (mCRC) liver tumor mic...

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Detalles Bibliográficos
Autores principales: Sathe, Anuja, Mason, Kaishu, Grimes, Susan M., Zhou, Zilu, Lau, Billy T., Bai, Xiangqi, Su, Andrew, Tan, Xiao, Lee, HoJoon, Suarez, Carlos J., Nguyen, Quan, Poultsides, George, Zhang, Nancy R., Ji, Hanlee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811165/
https://www.ncbi.nlm.nih.gov/pubmed/36239989
http://dx.doi.org/10.1158/1078-0432.CCR-22-2041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811165/
https://www.ncbi.nlm.nih.gov/pubmed/36239989
http://dx.doi.org/10.1158/1078-0432.CCR-22-2041

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