The immune microenvironment shapes transcriptional and genetic heterogeneity in chronic lymphocytic leukemia

In chronic lymphocytic leukemia (CLL), B-cell receptor signaling, tumor–microenvironment interactions, and somatic mutations drive disease progression. To better understand the intersection between the microenvironment and molecular events in CLL pathogenesis, we integrated bulk transcriptome profil...

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Detalles Bibliográficos
Autores principales: Sun, Clare, Chen, Yun-Ching, Martinez Zurita, Aina, Baptista, Maria Joao, Pittaluga, Stefania, Liu, Delong, Rosebrock, Daniel, Gohil, Satyen Harish, Saba, Nakhle S., Davies-Hill, Theresa, Herman, Sarah E. M., Getz, Gad, Pirooznia, Mehdi, Wu, Catherine J., Wiestner, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811214/
https://www.ncbi.nlm.nih.gov/pubmed/35358998
http://dx.doi.org/10.1182/bloodadvances.2021006941

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