TRPM1 promotes tumor progression in acral melanoma by activating the Ca(2+)/CaMKIIδ/AKT pathway

INTRODUCTION: Acral melanoma is a predominant and aggressive subtype of melanoma in non-Caucasian populations. There is a lack of genotype-driven therapies for over 50% of patients. TRPM1 (transient receptor potential melastatin 1), a nonspecific cation channel, is mainly expressed in retinal bipola...

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Detalles Bibliográficos
Autores principales: Hsieh, Chi-Che, Su, Yue-Chiu, Jiang, Kuan-Ying, Ito, Takamichi, Li, Ting-Wei, Kaku-Ito, Yumiko, Cheng, Shih-Tsung, Chen, Li-Tzong, Hwang, Daw-Yang, Shen, Che-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811324/
https://www.ncbi.nlm.nih.gov/pubmed/36585114
http://dx.doi.org/10.1016/j.jare.2022.03.005

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