GPX4 deficiency-dependent phospholipid peroxidation drives motor deficits of ALS

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by oxidative stress that triggers motor neurons loss in the brain and spinal cord. However, the mechanisms underlying the exact role of oxidative stress in ALS-associated neural degeneration are not definiti...

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Detalles Bibliográficos
Autores principales: Tu, Long-Fang, Zhang, Tian-Ze, Zhou, Yang-Fan, Zhou, Qing-Qing, Gong, Hai-Biao, Liang, Lei, Hai, Lin-Na, You, Nan-Xin, Su, Yang, Chen, Yong-Jun, Mo, Xu-Kai, Shi, Chang-Zheng, Luo, Liang-Ping, Sun, Wan-Yang, Duan, Wen-Jun, Kurihara, Hiroshi, Li, Yi-Fang, He, Rong-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811330/
https://www.ncbi.nlm.nih.gov/pubmed/36585109
http://dx.doi.org/10.1016/j.jare.2022.02.016

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