Optimized integration of metabolomics and lipidomics reveals brain region-specific changes of oxidative stress and neuroinflammation in type 1 diabetic mice with cognitive decline

INTRODUCTION: Type 1 diabetes (T1D) causes cognitive decline and has been associated with brain metabolic disorders, but its potential molecular mechanisms remain unclear. OBJECTIVES: The purpose of this study was to explore the molecular mechanisms underlying T1D-induced cognitive impairment using...

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Detalles Bibliográficos
Autores principales: Xiong, Fen, Gong, Kaiyan, Xu, Hangying, Tu, Yingxin, Lu, Jiahui, Zhou, Yiyang, He, Wenting, Li, Wenqing, Li, Chen, Zhao, Liangcai, Gao, Hongchang, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811331/
https://www.ncbi.nlm.nih.gov/pubmed/36585111
http://dx.doi.org/10.1016/j.jare.2022.02.011

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