The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells

Antibody secretion by plasma cells provides acute and long-term protection against pathogens. The high secretion potential of plasma cells depends on the unfolded protein response, which is controlled by the transcription factor Xbp1. Here, we analyzed the Xbp1-dependent gene expression program of p...

Descripción completa

Detalles Bibliográficos
Autores principales: Wöhner, Miriam, Pinter, Theresa, Bönelt, Peter, Hagelkruys, Astrid, Kostanova-Poliakova, Daniela, Stadlmann, Johannes, Konieczny, Stephen F., Fischer, Maria, Jaritz, Markus, Busslinger, Meinrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811352/
https://www.ncbi.nlm.nih.gov/pubmed/36618345
http://dx.doi.org/10.3389/fimmu.2022.859598

Ejemplares similares

Ejemplares similares