Identification of oxidosqualene cyclases associated with saponin biosynthesis from Astragalus membranaceus reveals a conserved motif important for catalytic function

INTRODUCTION: Triterpenoids and saponins have a broad range of pharmacological activities. Unlike most legumes which contain mainly oleanane-type scaffold, Astragalus membranaceus contains not only oleanane-type but also cycloartane-type saponins, for which the biosynthetic pathways are unknown. OBJ...

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Detalles Bibliográficos
Autores principales: Chen, Kuan, Zhang, Meng, Xu, Lulu, Yi, Yang, Wang, Linlin, Wang, Haotian, Wang, Zilong, Xing, Jiangtao, Li, Pi, Zhang, Xiaohui, Shi, Xiaomeng, Ye, Min, Osbourn, Anne, Qiao, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811366/
https://www.ncbi.nlm.nih.gov/pubmed/36585112
http://dx.doi.org/10.1016/j.jare.2022.03.014

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