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PEGylation and folic-acid functionalization of cationic lipoplexes—Improved nucleic acid transfer into cancer cells

Efficient and reliable transfer of nucleic acids for therapy applications is a major challenge. Stabilization of lipo- and polyplexes has already been successfully achieved by PEGylation. This modification reduces the interaction with serum proteins and thus prevents the lipoplexes from being cleare...

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Detalles Bibliográficos
Autores principales:	Hoffmann, Marco, Gerlach, Sven, Hoffmann, Christina, Richter, Nathalie, Hersch, Nils, Csiszár, Agnes, Merkel, Rudolf, Hoffmann, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811411/ https://www.ncbi.nlm.nih.gov/pubmed/36619382 http://dx.doi.org/10.3389/fbioe.2022.1066887

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