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Benefits of an Immunogenic Personalized Neoantigen Nanovaccine in Patients with High‐Risk Gastric/Gastroesophageal Junction Cancer (Adv. Sci. 1/2023)
Nanovaccine In article number 2203298, Baorui Liu, Jia Wei, and co‐workers prepare a personalized neoantigen nanovaccine (PNVAC) which spatially displays impressively enhanced lymph nodes trafficking capacity, and functionally induces more mature dendritic cells (DCs), neoantigen‐specific T cells, a...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811463/ http://dx.doi.org/10.1002/advs.202370001 |
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author | Liu, Qin Chu, Yanhong Shao, Jie Qian, Hanqing Yang, Ju Sha, Huizi Cen, Lanqi Tian, Manman Xu, Qiuping Chen, Fangjun Yang, Yang Wang, Weifeng Wang, Kai Yu, Lixia Wei, Jia Liu, Baorui |
author_facet | Liu, Qin Chu, Yanhong Shao, Jie Qian, Hanqing Yang, Ju Sha, Huizi Cen, Lanqi Tian, Manman Xu, Qiuping Chen, Fangjun Yang, Yang Wang, Weifeng Wang, Kai Yu, Lixia Wei, Jia Liu, Baorui |
author_sort | Liu, Qin |
collection | PubMed |
description | Nanovaccine In article number 2203298, Baorui Liu, Jia Wei, and co‐workers prepare a personalized neoantigen nanovaccine (PNVAC) which spatially displays impressively enhanced lymph nodes trafficking capacity, and functionally induces more mature dendritic cells (DCs), neoantigen‐specific T cells, and memory effector T cells. The PNVAC demonstrates superior protective efficacy against advanced gastric cancer recurrence and longer survival in preclinical studies and a phase I clinical trial. [Image: see text] |
format | Online Article Text |
id | pubmed-9811463 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98114632023-01-05 Benefits of an Immunogenic Personalized Neoantigen Nanovaccine in Patients with High‐Risk Gastric/Gastroesophageal Junction Cancer (Adv. Sci. 1/2023) Liu, Qin Chu, Yanhong Shao, Jie Qian, Hanqing Yang, Ju Sha, Huizi Cen, Lanqi Tian, Manman Xu, Qiuping Chen, Fangjun Yang, Yang Wang, Weifeng Wang, Kai Yu, Lixia Wei, Jia Liu, Baorui Adv Sci (Weinh) Cover Picture Nanovaccine In article number 2203298, Baorui Liu, Jia Wei, and co‐workers prepare a personalized neoantigen nanovaccine (PNVAC) which spatially displays impressively enhanced lymph nodes trafficking capacity, and functionally induces more mature dendritic cells (DCs), neoantigen‐specific T cells, and memory effector T cells. The PNVAC demonstrates superior protective efficacy against advanced gastric cancer recurrence and longer survival in preclinical studies and a phase I clinical trial. [Image: see text] John Wiley and Sons Inc. 2023-01-04 /pmc/articles/PMC9811463/ http://dx.doi.org/10.1002/advs.202370001 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Cover Picture Liu, Qin Chu, Yanhong Shao, Jie Qian, Hanqing Yang, Ju Sha, Huizi Cen, Lanqi Tian, Manman Xu, Qiuping Chen, Fangjun Yang, Yang Wang, Weifeng Wang, Kai Yu, Lixia Wei, Jia Liu, Baorui Benefits of an Immunogenic Personalized Neoantigen Nanovaccine in Patients with High‐Risk Gastric/Gastroesophageal Junction Cancer (Adv. Sci. 1/2023) |
title | Benefits of an Immunogenic Personalized Neoantigen Nanovaccine in Patients with High‐Risk Gastric/Gastroesophageal Junction Cancer (Adv. Sci. 1/2023) |
title_full | Benefits of an Immunogenic Personalized Neoantigen Nanovaccine in Patients with High‐Risk Gastric/Gastroesophageal Junction Cancer (Adv. Sci. 1/2023) |
title_fullStr | Benefits of an Immunogenic Personalized Neoantigen Nanovaccine in Patients with High‐Risk Gastric/Gastroesophageal Junction Cancer (Adv. Sci. 1/2023) |
title_full_unstemmed | Benefits of an Immunogenic Personalized Neoantigen Nanovaccine in Patients with High‐Risk Gastric/Gastroesophageal Junction Cancer (Adv. Sci. 1/2023) |
title_short | Benefits of an Immunogenic Personalized Neoantigen Nanovaccine in Patients with High‐Risk Gastric/Gastroesophageal Junction Cancer (Adv. Sci. 1/2023) |
title_sort | benefits of an immunogenic personalized neoantigen nanovaccine in patients with high‐risk gastric/gastroesophageal junction cancer (adv. sci. 1/2023) |
topic | Cover Picture |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811463/ http://dx.doi.org/10.1002/advs.202370001 |
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