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Emulating nonribosomal peptides with ribosomal biosynthetic strategies
Peptide natural products are important lead structures for human drugs and many nonribosomal peptides possess antibiotic activity. This makes them interesting targets for engineering approaches to generate peptide analogues with, for example, increased bioactivities. Nonribosomal peptides are produc...
Autores principales: | Mordhorst, Silja, Ruijne, Fleur, Vagstad, Anna L., Kuipers, Oscar P., Piel, Jörn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811515/ https://www.ncbi.nlm.nih.gov/pubmed/36685251 http://dx.doi.org/10.1039/d2cb00169a |
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