Synthesis and immunopharmacological evaluation of novel TLR7 agonistic triazole tethered imidazoquinolines

Toll-like receptors-7 and -8 are expressed abundantly on antigen-presenting cells, and their agonists make potential adjuvant candidates for the development of new efficacious vaccines. In view of the importance of new efficacious imidazoquinoline based adjuvants, herein we have synthesized a focuse...

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Detalles Bibliográficos
Autores principales: Avoni, Ayyappa, Vemireddy, Sravanthi, Sambyal, Shainy, Shafi, Syed, Khan, Imran, Khan, Aarif, Sampath Kumar, Halmuthur M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811562/
https://www.ncbi.nlm.nih.gov/pubmed/36686935
http://dx.doi.org/10.1039/d2ra06395f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811562/
https://www.ncbi.nlm.nih.gov/pubmed/36686935
http://dx.doi.org/10.1039/d2ra06395f

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