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SIRT3 inhibition suppresses hypoxia‐inducible factor 1α signaling and alleviates hypoxia‐induced apoptosis of type B spermatogonia GC‐2 cells

Hypoxia has been reported to be an important factor leading to male infertility, and it has been reported that hypoxia can induce the apoptosis of mouse spermatogenic cells. Sirtuin 3 (SIRT3) has been reported to promote the degradation of hypoxia‐inducible factor 1α (HIF‐1α), and thus, we hypothesi...

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Detalles Bibliográficos
Autores principales: Wang, Zixuan, Zhu, Chunchun, Song, Yangyang, Chen, Xiaoyun, Zheng, Jie, He, Lian, Liu, Xing, Chen, Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811653/
https://www.ncbi.nlm.nih.gov/pubmed/36383055
http://dx.doi.org/10.1002/2211-5463.13523