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Protocol for Evaluating In Vivo the Activation of the P2RX7 Immunomodulator

BACKGROUND: P2RX7 is a purinergic receptor with pleiotropic activities that is activated by high levels of extracellular ATP that are found in inflamed tissues. P2RX7 has immunomodulatory and anti-tumor proprieties and is therefore a therapeutic target for various diseases. Several compounds are dev...

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Detalles Bibliográficos
Autores principales:	Janho dit Hreich, Serena, Juhel, Thierry, Hofman, Paul, Vouret-Craviari, Valérie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811721/ https://www.ncbi.nlm.nih.gov/pubmed/36600200 http://dx.doi.org/10.1186/s12575-022-00188-6

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