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APOE effects on regional tau in preclinical Alzheimer’s disease

BACKGROUND: APOE variants are strongly associated with abnormal amyloid aggregation and additional direct effects of APOE on tau aggregation are reported in animal and human cell models. The degree to which these effects are present in humans when individuals are clinically unimpaired (CU) but have...

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Detalles Bibliográficos
Autores principales:	Young, Christina B., Johns, Emily, Kennedy, Gabriel, Belloy, Michael E., Insel, Philip S., Greicius, Michael D., Sperling, Reisa A., Johnson, Keith A., Poston, Kathleen L., Mormino, Elizabeth C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811772/ https://www.ncbi.nlm.nih.gov/pubmed/36597122 http://dx.doi.org/10.1186/s13024-022-00590-4

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