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Pentacam corneal topography and densitometry features of PCOS patients

BACKGROUND: To evaluate corneal topography and densitometry features in patients with polycystic ovary syndrome (PCOS) and compare them with healthy individuals. METHODS: 53 eyes of 53 female patients diagnosed with PCOS and 53 eyes of 53 age-matched female volunteers were analyzed in the study. In...

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Autores principales: Cengiz Ozturk, Tugce Gizem, Akcam, Hanife Tuba, Ellibes Kaya, Aski
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811775/
https://www.ncbi.nlm.nih.gov/pubmed/36597084
http://dx.doi.org/10.1186/s12886-022-02758-4
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author Cengiz Ozturk, Tugce Gizem
Akcam, Hanife Tuba
Ellibes Kaya, Aski
author_facet Cengiz Ozturk, Tugce Gizem
Akcam, Hanife Tuba
Ellibes Kaya, Aski
author_sort Cengiz Ozturk, Tugce Gizem
collection PubMed
description BACKGROUND: To evaluate corneal topography and densitometry features in patients with polycystic ovary syndrome (PCOS) and compare them with healthy individuals. METHODS: 53 eyes of 53 female patients diagnosed with PCOS and 53 eyes of 53 age-matched female volunteers were analyzed in the study. In addition to the detailed ophthalmological and gynecological examination, anterior segment analysis was performed using Pentacam. A complete analysis of aberrometric, keratometric, topometric, and, densitometric values between the groups was performed, and the results were outlined. RESULTS: According to the results, although Kmax-front, Kmean-front, ISV, IVA, IHA, BAD_D and PI-Avg values were slightly higher in PCOS group along with a slight thinning in the thinnest location, there was no statistically significant difference between the groups. Moreover, correlation analysis between PCOS clinical parameters and keratometric/topometric/aberrometric data were found to be almost normal. Yet, when Pentacam tomography maps of all cases are examined in detail, mild ectatic changes were observed in 5 cases in PCOS group. Furthermore, a significant increase in thickness across all densitometry values except anterior (10–12 mm), central (10–12 mm), and total (10–12 mm) was found in PCOS group. CONCLUSIONS: Our study showed that an intensification of corneal densitometry values ​​and various changes in keratometry data implying ectasia can be observed in patients with PCOS. Prospective studies with larger patient series are needed to reveal any potential relationship between PCOS and corneal abnormalities.
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spelling pubmed-98117752023-01-05 Pentacam corneal topography and densitometry features of PCOS patients Cengiz Ozturk, Tugce Gizem Akcam, Hanife Tuba Ellibes Kaya, Aski BMC Ophthalmol Research BACKGROUND: To evaluate corneal topography and densitometry features in patients with polycystic ovary syndrome (PCOS) and compare them with healthy individuals. METHODS: 53 eyes of 53 female patients diagnosed with PCOS and 53 eyes of 53 age-matched female volunteers were analyzed in the study. In addition to the detailed ophthalmological and gynecological examination, anterior segment analysis was performed using Pentacam. A complete analysis of aberrometric, keratometric, topometric, and, densitometric values between the groups was performed, and the results were outlined. RESULTS: According to the results, although Kmax-front, Kmean-front, ISV, IVA, IHA, BAD_D and PI-Avg values were slightly higher in PCOS group along with a slight thinning in the thinnest location, there was no statistically significant difference between the groups. Moreover, correlation analysis between PCOS clinical parameters and keratometric/topometric/aberrometric data were found to be almost normal. Yet, when Pentacam tomography maps of all cases are examined in detail, mild ectatic changes were observed in 5 cases in PCOS group. Furthermore, a significant increase in thickness across all densitometry values except anterior (10–12 mm), central (10–12 mm), and total (10–12 mm) was found in PCOS group. CONCLUSIONS: Our study showed that an intensification of corneal densitometry values ​​and various changes in keratometry data implying ectasia can be observed in patients with PCOS. Prospective studies with larger patient series are needed to reveal any potential relationship between PCOS and corneal abnormalities. BioMed Central 2023-01-03 /pmc/articles/PMC9811775/ /pubmed/36597084 http://dx.doi.org/10.1186/s12886-022-02758-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Cengiz Ozturk, Tugce Gizem
Akcam, Hanife Tuba
Ellibes Kaya, Aski
Pentacam corneal topography and densitometry features of PCOS patients
title Pentacam corneal topography and densitometry features of PCOS patients
title_full Pentacam corneal topography and densitometry features of PCOS patients
title_fullStr Pentacam corneal topography and densitometry features of PCOS patients
title_full_unstemmed Pentacam corneal topography and densitometry features of PCOS patients
title_short Pentacam corneal topography and densitometry features of PCOS patients
title_sort pentacam corneal topography and densitometry features of pcos patients
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811775/
https://www.ncbi.nlm.nih.gov/pubmed/36597084
http://dx.doi.org/10.1186/s12886-022-02758-4
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