Ferritin-induced NETs lead to cytokine storm in AOSD

New research reveals that ferritin has an essential role in neutrophil extracellular trap (NET)-mediated inflammation, and suggests that NETs or the ferritin receptor MSR1 could be targeted for the treatment of adult-onset Still disease.

Detalles Bibliográficos
Autor principal: Onuora, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811892/
https://www.ncbi.nlm.nih.gov/pubmed/36600114
http://dx.doi.org/10.1038/s41584-022-00899-w
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author Onuora, Sarah
author_facet Onuora, Sarah
author_sort Onuora, Sarah
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description New research reveals that ferritin has an essential role in neutrophil extracellular trap (NET)-mediated inflammation, and suggests that NETs or the ferritin receptor MSR1 could be targeted for the treatment of adult-onset Still disease.
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spelling pubmed-98118922023-01-04 Ferritin-induced NETs lead to cytokine storm in AOSD Onuora, Sarah Nat Rev Rheumatol Research Highlight New research reveals that ferritin has an essential role in neutrophil extracellular trap (NET)-mediated inflammation, and suggests that NETs or the ferritin receptor MSR1 could be targeted for the treatment of adult-onset Still disease. Nature Publishing Group UK 2023-01-04 2023 /pmc/articles/PMC9811892/ /pubmed/36600114 http://dx.doi.org/10.1038/s41584-022-00899-w Text en © Springer Nature Limited 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Highlight
Onuora, Sarah
Ferritin-induced NETs lead to cytokine storm in AOSD
title Ferritin-induced NETs lead to cytokine storm in AOSD
title_full Ferritin-induced NETs lead to cytokine storm in AOSD
title_fullStr Ferritin-induced NETs lead to cytokine storm in AOSD
title_full_unstemmed Ferritin-induced NETs lead to cytokine storm in AOSD
title_short Ferritin-induced NETs lead to cytokine storm in AOSD
title_sort ferritin-induced nets lead to cytokine storm in aosd
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811892/
https://www.ncbi.nlm.nih.gov/pubmed/36600114
http://dx.doi.org/10.1038/s41584-022-00899-w
work_keys_str_mv AT onuorasarah ferritininducednetsleadtocytokinestorminaosd

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