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Laser flare photometry in uveitis
Aqueous flare and cells are inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood-ocular barrier. The ocular inflammation related to anterior chamber cells and flare is assessed by conventional clinical grading systems through using the slit-lamp examination...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811932/ https://www.ncbi.nlm.nih.gov/pubmed/36618569 http://dx.doi.org/10.4103/sjopt.sjopt_119_22 |
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author | Kesim, Cem Chehab, Zahed Hasanreisoglu, Murat |
author_facet | Kesim, Cem Chehab, Zahed Hasanreisoglu, Murat |
author_sort | Kesim, Cem |
collection | PubMed |
description | Aqueous flare and cells are inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood-ocular barrier. The ocular inflammation related to anterior chamber cells and flare is assessed by conventional clinical grading systems through using the slit-lamp examination. However, a more quantitative and objective assessment is needed for more precise and reproducible inflammatory assessment in uveitis. Laser flare photometer (LFP) was introduced as a noninvasive, objective, and quantitative evaluation of aqueous flare intensity and number of cells in the anterior chamber with good accuracy and repeatability. The success of LFP allowed clinicians to further evaluate the pathophysiology of intra-ocular inflammation and to incorporate LFP measurements to their routine clinical practice for diagnosis, management, and treatment of uveitis cases. In this review, we will discuss the importance of clinical utilization of LFP and the correlation between LFP and clinical grading systems along with some technical aspects. Furthermore, we will give a literature summary on the current applications of LFP in clinical practice of cases which present with various types of uveitis and diverse ocular conditions with or without inflammation. |
format | Online Article Text |
id | pubmed-9811932 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-98119322023-01-05 Laser flare photometry in uveitis Kesim, Cem Chehab, Zahed Hasanreisoglu, Murat Saudi J Ophthalmol New Developments in Uveitis Aqueous flare and cells are inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood-ocular barrier. The ocular inflammation related to anterior chamber cells and flare is assessed by conventional clinical grading systems through using the slit-lamp examination. However, a more quantitative and objective assessment is needed for more precise and reproducible inflammatory assessment in uveitis. Laser flare photometer (LFP) was introduced as a noninvasive, objective, and quantitative evaluation of aqueous flare intensity and number of cells in the anterior chamber with good accuracy and repeatability. The success of LFP allowed clinicians to further evaluate the pathophysiology of intra-ocular inflammation and to incorporate LFP measurements to their routine clinical practice for diagnosis, management, and treatment of uveitis cases. In this review, we will discuss the importance of clinical utilization of LFP and the correlation between LFP and clinical grading systems along with some technical aspects. Furthermore, we will give a literature summary on the current applications of LFP in clinical practice of cases which present with various types of uveitis and diverse ocular conditions with or without inflammation. Wolters Kluwer - Medknow 2022-12-27 /pmc/articles/PMC9811932/ /pubmed/36618569 http://dx.doi.org/10.4103/sjopt.sjopt_119_22 Text en Copyright: © 2022 Saudi Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | New Developments in Uveitis Kesim, Cem Chehab, Zahed Hasanreisoglu, Murat Laser flare photometry in uveitis |
title | Laser flare photometry in uveitis |
title_full | Laser flare photometry in uveitis |
title_fullStr | Laser flare photometry in uveitis |
title_full_unstemmed | Laser flare photometry in uveitis |
title_short | Laser flare photometry in uveitis |
title_sort | laser flare photometry in uveitis |
topic | New Developments in Uveitis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811932/ https://www.ncbi.nlm.nih.gov/pubmed/36618569 http://dx.doi.org/10.4103/sjopt.sjopt_119_22 |
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