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Laser flare photometry in uveitis

Aqueous flare and cells are inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood-ocular barrier. The ocular inflammation related to anterior chamber cells and flare is assessed by conventional clinical grading systems through using the slit-lamp examination...

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Autores principales: Kesim, Cem, Chehab, Zahed, Hasanreisoglu, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811932/
https://www.ncbi.nlm.nih.gov/pubmed/36618569
http://dx.doi.org/10.4103/sjopt.sjopt_119_22
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author Kesim, Cem
Chehab, Zahed
Hasanreisoglu, Murat
author_facet Kesim, Cem
Chehab, Zahed
Hasanreisoglu, Murat
author_sort Kesim, Cem
collection PubMed
description Aqueous flare and cells are inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood-ocular barrier. The ocular inflammation related to anterior chamber cells and flare is assessed by conventional clinical grading systems through using the slit-lamp examination. However, a more quantitative and objective assessment is needed for more precise and reproducible inflammatory assessment in uveitis. Laser flare photometer (LFP) was introduced as a noninvasive, objective, and quantitative evaluation of aqueous flare intensity and number of cells in the anterior chamber with good accuracy and repeatability. The success of LFP allowed clinicians to further evaluate the pathophysiology of intra-ocular inflammation and to incorporate LFP measurements to their routine clinical practice for diagnosis, management, and treatment of uveitis cases. In this review, we will discuss the importance of clinical utilization of LFP and the correlation between LFP and clinical grading systems along with some technical aspects. Furthermore, we will give a literature summary on the current applications of LFP in clinical practice of cases which present with various types of uveitis and diverse ocular conditions with or without inflammation.
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spelling pubmed-98119322023-01-05 Laser flare photometry in uveitis Kesim, Cem Chehab, Zahed Hasanreisoglu, Murat Saudi J Ophthalmol New Developments in Uveitis Aqueous flare and cells are inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood-ocular barrier. The ocular inflammation related to anterior chamber cells and flare is assessed by conventional clinical grading systems through using the slit-lamp examination. However, a more quantitative and objective assessment is needed for more precise and reproducible inflammatory assessment in uveitis. Laser flare photometer (LFP) was introduced as a noninvasive, objective, and quantitative evaluation of aqueous flare intensity and number of cells in the anterior chamber with good accuracy and repeatability. The success of LFP allowed clinicians to further evaluate the pathophysiology of intra-ocular inflammation and to incorporate LFP measurements to their routine clinical practice for diagnosis, management, and treatment of uveitis cases. In this review, we will discuss the importance of clinical utilization of LFP and the correlation between LFP and clinical grading systems along with some technical aspects. Furthermore, we will give a literature summary on the current applications of LFP in clinical practice of cases which present with various types of uveitis and diverse ocular conditions with or without inflammation. Wolters Kluwer - Medknow 2022-12-27 /pmc/articles/PMC9811932/ /pubmed/36618569 http://dx.doi.org/10.4103/sjopt.sjopt_119_22 Text en Copyright: © 2022 Saudi Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle New Developments in Uveitis
Kesim, Cem
Chehab, Zahed
Hasanreisoglu, Murat
Laser flare photometry in uveitis
title Laser flare photometry in uveitis
title_full Laser flare photometry in uveitis
title_fullStr Laser flare photometry in uveitis
title_full_unstemmed Laser flare photometry in uveitis
title_short Laser flare photometry in uveitis
title_sort laser flare photometry in uveitis
topic New Developments in Uveitis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811932/
https://www.ncbi.nlm.nih.gov/pubmed/36618569
http://dx.doi.org/10.4103/sjopt.sjopt_119_22
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