Adjunctive use of p16 immunohistochemistry for optimizing management of CIN lesions in a high‐risk human papillomavirus‐positive population

INTRODUCTION: Immunostaining with p16(INK4a) (p16), a tumor‐suppressor surrogate protein biomarker for high‐risk human papillomavirus (hrHPV) oncogenic activity, may complement standard hematoxylin and eosin (H&E) histology review, and provide more objective criteria to support the cervical intr...

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Detalles Bibliográficos
Autores principales: Ebisch, Renée M. F., Rijstenberg, L. Lucia, Soltani, Gilda Ghazi, van der Horst, Judith, Vedder, Judith E. M., Hermsen, Meyke, Bosgraaf, Remko P., Massuger, Leon F. A. G., Meijer, Chris J. L. M., Heideman, Daniëlle A. M., van Kemenade, Folkert J., Melchers, Willem J. G., Bekkers, Ruud L. M., Siebers, Albert G., Bulten, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812205/
https://www.ncbi.nlm.nih.gov/pubmed/36177908
http://dx.doi.org/10.1111/aogs.14459

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