Cargando…

Curcumin’s mechanism of action against ischemic stroke: A network pharmacology and molecular dynamics study

Ischemic stroke (IS) is one of the major global causes of death and disability. Because blood clots block the neural arteries provoking ischemia and hypoxia in the brain tissue, IS results in irreversible neurological damage. Available IS treatments are currently limited. Curcumin has gained attenti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yangyang, Zu, Guoxiu, Yu, Ying, Tang, Jiqin, Han, Tao, Zhang, Chengdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812305/ https://www.ncbi.nlm.nih.gov/pubmed/36598916 http://dx.doi.org/10.1371/journal.pone.0280112

Ejemplares similares

Exploring the molecular mechanism of Nux Vomica in treating ischemic stroke using network pharmacology and molecular docking methods
por: Zhang, Chengdong, et al.
Publicado: (2023)

Understanding the molecular mechanism of Ginkgo Folium-Forsythiae Fructus for cerebral atherosclerosis treatment using network pharmacology and molecular docking
por: Zhang, Jinfei, et al.
Publicado: (2023)

Exploration of potential targets and mechanisms of Naringenin in treating autism spectrum disorder via network pharmacology and molecular docking
por: Gai, Jialin, et al.
Publicado: (2022)

Pharmacological intervention of curcumin via the NLRP3 inflammasome in ischemic stroke
por: Du, Xiaoxue, et al.
Publicado: (2023)

Molecular Mechanism of Epimedium Extract against Ischemic Stroke Based on Network Pharmacology and Experimental Validation
por: Xu, Hongbei, et al.
Publicado: (2022)

Exploring the mechanism of Ginkgo biloba L. leaves in the treatment of vascular dementia based on network pharmacology, molecular docking, and molecular dynamics simulation
por: Pan, Jienuo, et al.
Publicado: (2023)

A network pharmacology approach to identify the mechanisms and molecular targets of curcumin against Alzheimer disease
por: Wu, Xinyan, et al.
Publicado: (2022)

Exploration of the mechanism of luteolin against ischemic stroke based on network pharmacology, molecular docking and experimental verification
por: Dong, Rui, et al.
Publicado: (2021)

Network pharmacology and molecular docking reveal the effective substances and active mechanisms of Dalbergia Odoriferain protecting against ischemic stroke
por: Liu, Kedi, et al.
Publicado: (2021)

Curcumin Protects against Ischemic Stroke by Titrating Microglia/Macrophage Polarization
por: Liu, Zongjian, et al.
Publicado: (2017)

Network pharmacology and molecular docking-based analysis of protective mechanism of MLIF in ischemic stroke
por: Lv, Mengting, et al.
Publicado: (2022)

Deep muscle stimulator in the treatment of post-stroke spasticity: A protocol for systematic review and meta-analysis
por: Lei, Junfang, et al.
Publicado: (2023)

Exploring the Mechanism of Curcumin on Retinoblastoma Based on Network Pharmacology and Molecular Docking
por: Wu, Chengfu, et al.
Publicado: (2022)

Systematic Understanding of the Mechanism of Baicalin against Ischemic Stroke through a Network Pharmacology Approach
por: Xu, Tian, et al.
Publicado: (2018)

Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of Buyang Huanwu Decoction in the Treatment of Ischemic Stroke
por: Gao, Qiang, et al.
Publicado: (2021)

Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Gastrodia elata Blume in the treatment of ischemic stroke
por: Luo, Yuan, et al.
Publicado: (2022)

Revealing the Pharmacological Mechanism of Acorus tatarinowii in the Treatment of Ischemic Stroke Based on Network Pharmacology
por: Liu, FengZhi, et al.
Publicado: (2020)

Corrigendum to “Systematic Understanding of the Mechanism of Baicalin against Ischemic Stroke through a Network Pharmacology Approach”
por: Xu, Tian, et al.
Publicado: (2019)

Curcumin protects neural cells against ischemic injury in N2a cells and mouse brain with ischemic stroke
por: Xie, Cai‐Jun, et al.
Publicado: (2018)

Exploring the Potential Mechanism of Shennao Fuyuan Tang for Ischemic Stroke Based on Network Pharmacology and Molecular Docking
por: Li, Jia Min, et al.
Publicado: (2021)

Multi-target mechanism of Naoshuantong capsule for treatment of Ischemic stroke based on network pharmacology and molecular docking
por: Yang, Fengjiao, et al.
Publicado: (2023)

Integration of molecular docking, molecular dynamics and network pharmacology to explore the multi‐target pharmacology of fenugreek against diabetes
por: Luo, Wenfeng, et al.
Publicado: (2023)

From single drug targets to synergistic network pharmacology in ischemic stroke
por: Casas, Ana I., et al.
Publicado: (2019)

Analysis of active components and molecular mechanism of action of Rubia cordifolia L. in the treatment of nasopharyngeal carcinoma based on network pharmacology and experimental verification
por: Yang, Ximing, et al.
Publicado: (2023)

Exploring the mechanism of curcumin in the treatment of colon cancer based on network pharmacology and molecular docking
por: He, Qingmin, et al.
Publicado: (2023)

Systematic Understanding of Mechanism of Danggui Shaoyao San against Ischemic Stroke Using a Network Pharmacology Approach
por: Li, Sijie, et al.
Publicado: (2022)

Key Phytochemicals and Biological Functions of Chuanxiong Rhizoma Against Ischemic Stroke: A Network Pharmacology and Experimental Assessment
por: Zeng, Peng, et al.
Publicado: (2021)

Exploring Active Compounds and Mechanisms of Angong Niuhuang Wan on Ischemic Stroke Based on Network Pharmacology and Molecular Docking
por: Zhang, Yasu, et al.
Publicado: (2022)

Investigation into the potential mechanism and molecular targets of Fufang Xueshuantong capsule for the treatment of ischemic stroke based on network pharmacology and molecular docking
por: Wang, Lei, et al.
Publicado: (2022)

Pharmacological and Non-Pharmacological Recanalization Strategies in Acute Ischemic Stroke
por: Frendl, Anita, et al.
Publicado: (2011)

A Network Pharmacology to Explore the Mechanism of Calculus Bovis in the Treatment of Ischemic Stroke
por: Liu, Fangchen, et al.
Publicado: (2021)

The Pharmacological Mechanism of Curcumin against Drug Resistance in Non-Small Cell Lung Cancer: Findings of Network Pharmacology and Bioinformatics Analysis
por: Xie, Han, et al.
Publicado: (2022)

Systems Pharmacology-Dissection of the Molecular Mechanisms of Dragon's Blood in Improving Ischemic Stroke Prognosis
por: Jiang, Meng, et al.
Publicado: (2020)

A Network Pharmacology Approach to Investigate the Active Compounds and Mechanisms of Musk for Ischemic Stroke
por: Zhang, Changlin, et al.
Publicado: (2020)

Mechanism of Salvia miltiorrhiza Bge. for the Treatment of Ischemic Stroke Based on Bioinformatics and Network Pharmacology
por: Wu, Jiaqi, et al.
Publicado: (2022)

Network Pharmacology-Based Prediction of Catalpol and Mechanisms against Stroke
por: Wang, Jinghui, et al.
Publicado: (2021)

Network Pharmacology-Based Approach to Revealing Biological Mechanisms of Qingkailing Injection against IschemicStroke: Focusing on Blood-Brain Barrier
por: Zhang, Shuang, et al.
Publicado: (2020)

Investigating the Protective Effect of Gross Saponins of Tribulus terrestris Fruit against Ischemic Stroke in Rat Using Metabolomics and Network Pharmacology
por: Wang, Yang, et al.
Publicado: (2019)

Uncovering the Mechanism of the Xingnaojing Injection against Ischemic Stroke Using a Combined Network Pharmacology Approach and Gut Microbiota Analysis
por: Liu, Ganlu, et al.
Publicado: (2022)

Exploring the Molecular Mechanism of Action of Yinchen Wuling Powder for the Treatment of Hyperlipidemia, Using Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation
por: Ye, Jiahao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mqhb4frmd1vmfd3ratetaku7jt