scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors

Single-cell multi-omics can provide a unique perspective on tumor cellular heterogeneity. Most previous single-cell whole-genome RNA sequencing (scWGS-RNA-seq) methods demonstrate utility with intact cells from fresh samples. Among them, many are not applicable to frozen samples that cannot produce...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Wang, Xinlei, Mu, Quanhua, Tam, Sindy Sing Ting, Loi, Danson Shek Chun, Chan, Aden K. Y., Poon, Wai Sang, Ng, Ho-Keung, Chan, Danny T. M., Wang, Jiguang, Wu, Angela Ruohao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812385/
https://www.ncbi.nlm.nih.gov/pubmed/36598983
http://dx.doi.org/10.1126/sciadv.abp8901

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