Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism

Tissue injury induces metabolic changes in stem cells, which likely modulate regeneration. Using a model of organ regeneration called wound-induced hair follicle neogenesis (WIHN), we identified skin-resident bacteria as key modulators of keratinocyte metabolism, demonstrating a positive correlation...

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Detalles Bibliográficos
Autores principales: Wang, Gaofeng, Sweren, Evan, Andrews, William, Li, Yue, Chen, Junjun, Xue, Yingchao, Wier, Eric, Alphonse, Martin P., Luo, Li, Miao, Yong, Chen, Ruosi, Zeng, Dongqiang, Lee, Sam, Li, Ang, Dare, Erika, Kim, Dongwon, Archer, Nathan K., Reddy, Sashank K., Resar, Linda, Hu, Zhiqi, Grice, Elizabeth A., Kane, Maureen A., Garza, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812389/
https://www.ncbi.nlm.nih.gov/pubmed/36598999
http://dx.doi.org/10.1126/sciadv.abo7555

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