Evaluation of Na(v)1.8 as a therapeutic target for Pitt Hopkins Syndrome

Pitt Hopkins Syndrome (PTHS) is a rare syndromic form of autism spectrum disorder (ASD) caused by autosomal dominant mutations in the Transcription Factor 4 (TCF4) gene. TCF4 is a basic helix-loop-helix transcription factor that is critical for neurodevelopment and brain function through its binding...

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Detalles Bibliográficos
Autores principales: Martinowich, Keri, Das, Debamitra, Sripathy, Srinidhi Rao, Mai, Yishan, Kenney, Rakaia F., Maher, Brady J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812766/
https://www.ncbi.nlm.nih.gov/pubmed/36224259
http://dx.doi.org/10.1038/s41380-022-01811-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812766/
https://www.ncbi.nlm.nih.gov/pubmed/36224259
http://dx.doi.org/10.1038/s41380-022-01811-4

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