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Inhibition of YAP Sensitizes the Selumetinib Treatment for Neurofibromatosis Type 1 Related Plexiform Neurofibroma

Background: Targeted therapy of Neurofibromatosis type 1 (NF1) related plexiform neurofibroma (pNF) aiming at MEK molecule has not demonstrated a convincing result for complete disease inhibition, probably due to other signal pathways crosstalk. Our previous study revealed an increased nuclear trans...

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Detalles Bibliográficos
Autores principales:	Tian, Zhuowei, You, Yuanhe, Xiao, Meng, Liu, Jialiang, Xu, Guisong, Ma, Chunyue, Du, Zhong, Wang, Yanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812799/ https://www.ncbi.nlm.nih.gov/pubmed/36619222 http://dx.doi.org/10.7150/ijms.78386

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