Cargando…
Neoadjuvant chemotherapy is associated with an altered metabolic profile and increased cancer stemness in patients with pancreatic ductal adenocarcinoma
The modest clinical benefits of neoadjuvant chemotherapy (NAT) in pancreatic ductal adenocarcinoma (PDAC) are associated with a lack of robust data on treatment‐induced changes in the tumor. To this end, comparative proteomic profiling of tumor tissue samples from treatment‐naïve (TN, n = 20) and NA...
Autores principales: | Amrutkar, Manoj, Verbeke, Caroline S., Finstadsveen, Anette Vefferstad, Dorg, Linda, Labori, Knut Jørgen, Gladhaug, Ivar P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812839/ https://www.ncbi.nlm.nih.gov/pubmed/36400567 http://dx.doi.org/10.1002/1878-0261.13344 |
Ejemplares similares
-
Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol flux in pancreatic cancer cells
por: Li, Yuchuan, et al.
Publicado: (2023) -
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence
por: Sántha, Petra, et al.
Publicado: (2021) -
Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing
por: Amrutkar, Manoj, et al.
Publicado: (2020) -
Establishment and Characterization of Paired Primary Cultures of Human Pancreatic Cancer Cells and Stellate Cells Derived from the Same Tumor
por: Amrutkar, Manoj, et al.
Publicado: (2020) -
Pancreatic stellate cell-induced gemcitabine resistance in pancreatic cancer is associated with LDHA- and MCT4-mediated enhanced glycolysis
por: Amrutkar, Manoj, et al.
Publicado: (2023)