Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients

Tumour acidosis contributes to cancer progression by inhibiting anti-tumour immunity. However, the effect of acidosis on anti-tumour T cell phenotypes in oesophageal adenocarcinoma (OAC) is unknown. Therefore, this study investigated the effect of acidosis on anti-tumour T cell profiles and if immun...

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Detalles Bibliográficos
Autores principales: Davern, Maria, Donlon, Noel E., O’Connell, Fiona, Gaughan, Caoimhe, O’Donovan, Cillian, Habash, Mohammed, Sheppard, Andrew D., MacLean, Michael, Dunne, Margaret R., Moore, Jenny, Temperley, Hugo, Conroy, Melissa J., Butler, Christine, Bhardwaj, Anshul, Ravi, Narayanasamy, Donohoe, Claire L., Reynolds, John V., Lysaght, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813044/
https://www.ncbi.nlm.nih.gov/pubmed/35708739
http://dx.doi.org/10.1007/s00262-022-03228-y

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