An oral WT1 protein vaccine composed of WT1-anchored, genetically engineered Bifidobacterium longum allows for intestinal immunity in mice with acute myeloid leukemia

Wilms’ tumor 1 (WT1) is a promising tumor-associated antigen for cancer immunotherapy. We developed an oral protein vaccine platform composed of WT1-anchored, genetically engineered Bifidobacterium longum (B. longum) and conducted an in vivo study in mice to examine its anticancer activity. Mice wer...

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Detalles Bibliográficos
Autores principales: Nakagawa, Natsuki, Hashii, Yoshiko, Kayama, Hisako, Okumura, Ryu, Nakajima, Hiroko, Minagawa, Hikaru, Morimoto, Soyoko, Fujiki, Fumihiro, Nakata, Jun, Shirakawa, Toshiro, Katayama, Takane, Takeda, Kiyoshi, Tsuboi, Akihiro, Ozono, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813063/
https://www.ncbi.nlm.nih.gov/pubmed/35699757
http://dx.doi.org/10.1007/s00262-022-03214-4

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