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Ubiquitous mitochondrial creatine kinase promotes the progression of gastric cancer through a JNK-MAPK/JUN/HK2 axis regulated glycolysis

BACKGROUND: Ubiquitous mitochondrial creatine kinase (uMtCK) transfers high-energy phosphates from mitochondrially generated ATP to creatine to generate phosphocreatine. uMtCK overexpression has been reported in several malignant tumors, however, the clinical significance and impact of uMtCK in gast...

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Detalles Bibliográficos
Autores principales: Mi, Yushuai, Li, Quanhui, Liu, Bingtian, Wang, Dehai, Liu, Ziping, Wang, Tianshi, Wang, Yuan, Zang, Yifeng, Zhou, Yan, Wen, Yugang, Ding, Yinlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813075/
https://www.ncbi.nlm.nih.gov/pubmed/36114400
http://dx.doi.org/10.1007/s10120-022-01340-7