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TIGIT blockade enhances tumor response to radiotherapy via a CD103 + dendritic cell-dependent mechanism

Blockade of the T cell immunoreceptor with the immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) can enhance innate and adaptive tumor immunity and radiotherapy (RT) can enhance anti-tumor immunity. However, our data suggest that TIGIT-mediated immune suppression may b...

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Detalles Bibliográficos
Autores principales:	Zhao, Kaikai, Jiang, Liyang, Si, Youjiao, Zhou, Shujie, Huang, Zhaoqin, Meng, Xiangjiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813151/ https://www.ncbi.nlm.nih.gov/pubmed/35794399 http://dx.doi.org/10.1007/s00262-022-03227-z

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