Cargando…
PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions
Polyglutamine binding protein 5 (PQBP5), also called nucleolar protein 10 (NOL10), binds to polyglutamine tract sequences and is expressed in the nucleolus. Using dynamic imaging of high-speed atomic force microscopy, we show that PQBP5/NOL10 is an intrinsically disordered protein. Super-resolution...
Autores principales: | Jin, Xiaocen, Tanaka, Hikari, Jin, Meihua, Fujita, Kyota, Homma, Hidenori, Inotsume, Maiko, Yong, Huang, Umeda, Kenichi, Kodera, Noriyuki, Ando, Toshio, Okazawa, Hitoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813255/ https://www.ncbi.nlm.nih.gov/pubmed/36599853 http://dx.doi.org/10.1038/s41467-022-35602-w |
Ejemplares similares
-
Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation
por: Jin, Meihua, et al.
Publicado: (2021) -
The intellectual disability gene PQBP1 rescues Alzheimer’s disease pathology
por: Tanaka, Hikari, et al.
Publicado: (2018) -
PQBP1: The Key to Intellectual Disability, Neurodegenerative Diseases, and Innate Immunity
por: Tanaka, Hikari, et al.
Publicado: (2022) -
Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis
por: Jin, Meihua, et al.
Publicado: (2021) -
Sox2 Transcriptionally Regulates Pqbp1, an Intellectual Disability-Microcephaly Causative Gene, in Neural Stem Progenitor Cells
por: Li, Chan, et al.
Publicado: (2013)