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Insights into the GSDMB-mediated cellular lysis and its targeting by IpaH7.8

The multifunctional GSDMB protein is an important molecule in human immunity. The pyroptotic and bactericidal activity of GSDMB is a host response to infection by the bacterial pathogen Shigella flexneri, which employs the virulence effector IpaH7.8 to ubiquitinate and target GSDMB for proteasome-de...

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Detalles Bibliográficos
Autores principales:	Yin, Hang, Zheng, Jian, He, Qiuqiu, Zhang, Xuan, Li, Xuzichao, Ma, Yongjian, Liang, Xiao, Gao, Jiaqi, Kocsis, Benjamin L., Li, Zhuang, Liu, Xiang, Alto, Neal M., Li, Long, Zhang, Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813358/ https://www.ncbi.nlm.nih.gov/pubmed/36599845 http://dx.doi.org/10.1038/s41467-022-35725-0

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