Cargando…

Poor prognostic implications of myelodysplasia-related mutations in both older and younger patients with de novo AML

A set of myelodysplasia-related (MDS-R) gene mutations are incorporated into the 2022 European LeukemiaNet risk classification as adverse genetic factors for acute myeloid leukemia (AML) based on their poor prognostic impact on older patients. The impact of these mutations on younger patients (age &...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsai, Xavier Cheng-Hong, Sun, Kuo-Jui, Lo, Min-Yen, Tien, Feng-Ming, Kuo, Yuan-Yeh, Tseng, Mei-Hsuan, Peng, Yen-Ling, Chuang, Yi-Kuang, Ko, Bor-Sheng, Tang, Jih-Luh, Sun, Hsun-I, Liu, Ming-Chih, Liu, Chia-Wen, Lin, Chien-Chin, Yao, Ming, Chou, Wen-Chien, Hou, Hsin-An, Tien, Hwei-Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813374/ https://www.ncbi.nlm.nih.gov/pubmed/36599822 http://dx.doi.org/10.1038/s41408-022-00774-7

Ejemplares similares

P721: VALIDATION OF THE MOLECULAR INTERNATIONAL PROGNOSTIC SCORING SYSTEM IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES DEFINED BY INTERNATIONAL CONSENSUS CLASSIFICATION
por: Hsuan Lee, Wan, et al.
Publicado: (2023)

Hierarchical cluster analysis of immunophenotype classify AML patients with NPM1 gene mutation into two groups with distinct prognosis
por: Chen, Chien-Yuan, et al.
Publicado: (2013)

Validation of the molecular international prognostic scoring system in patients with myelodysplastic syndromes defined by international consensus classification
por: Lee, Wan-Hsuan, et al.
Publicado: (2023)

An mRNA expression signature for prognostication in de novo acute myeloid leukemia patients with normal karyotype
por: Chuang, Ming-Kai, et al.
Publicado: (2015)

Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia
por: Hou, Hsin-An, et al.
Publicado: (2016)

Incorporation of mutations in five genes in the revised International Prognostic Scoring System can improve risk stratification in the patients with myelodysplastic syndrome
por: Hou, Hsin-An, et al.
Publicado: (2018)

Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients
por: Tsai, Cheng-Hong, et al.
Publicado: (2019)

Prognostic impacts and dynamic changes of cohesin complex gene mutations in de novo acute myeloid leukemia
por: Tsai, Cheng-Hong, et al.
Publicado: (2017)

De novo AML exhibits greater microenvironment dysregulation compared to AML with myelodysplasia-related changes
por: Lopes, Matheus Rodrigues, et al.
Publicado: (2017)

GATA2 zinc finger 1 mutations are associated with distinct clinico-biological features and outcomes different from GATA2 zinc finger 2 mutations in adult acute myeloid leukemia
por: Tien, Feng-Ming, et al.
Publicado: (2018)

Hepatitis B reactivation among 1962 patients with hematological malignancy in Taiwan
por: Chen, Chien-Yuan, et al.
Publicado: (2018)

Dynamics of DNMT3A mutation and prognostic relevance in patients with primary myelodysplastic syndrome
por: Lin, Ming-En, et al.
Publicado: (2018)

UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome
por: Georgi, Julia-Annabell, et al.
Publicado: (2023)

High Risk of Hepatitis B Reactivation among Patients with Acute Myeloid Leukemia
por: Chen, Chien-Yuan, et al.
Publicado: (2015)

A three-gene expression-based risk score can refine the European LeukemiaNet AML classification
por: Wilop, Stefan, et al.
Publicado: (2016)

ASXL1 mutation confers poor prognosis in primary myelofibrosis patients with low JAK2V617F allele burden but not in those with high allele burden
por: Wang, Yu-Hung, et al.
Publicado: (2020)

Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes (h-MDS)
por: Yao, Chi-Yuan, et al.
Publicado: (2016)

AML with Myelodysplasia-Related Changes: Development, Challenges, and Treatment Advances
por: Koenig, Kristin L., et al.
Publicado: (2020)

Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome
por: Huang, Huai-Hsuan, et al.
Publicado: (2019)

Higher HOPX expression is associated with distinct clinical and biological features and predicts poor prognosis in de novo acute myeloid leukemia
por: Lin, Chien-Chin, et al.
Publicado: (2017)

Busulfan‐containing conditioning regimens in allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia: A Taiwan observational study
por: Wang, Yu‐Hung, et al.
Publicado: (2021)

Clinical and Prognostic Implications of Roundabout 4 (Robo4) in Adult Patients with Acute Myeloid Leukemia
por: Chen, Yin-Kai, et al.
Publicado: (2015)

Screening for myeloid mutations in patients with myelodysplastic syndromes and AML with myelodysplasia-related changes
por: Bezerra, Matheus F., et al.
Publicado: (2022)

S131: CLINICAL IMPLICATIONS OF SECONDARY-AML TYPE MUTATIONS IN PATIENTS WITH DE NOVO ACUTE MYELOID LEUKEMIA
por: Sun, K., et al.
Publicado: (2022)

Uncovering Clinical Features of De Novo Philadelphia Positive Myelodysplasia
por: Armas, Aristides, et al.
Publicado: (2017)

Intracranial hemorrhage in adult patients with hematological malignancies
por: Chen, Chien-Yuan, et al.
Publicado: (2012)

Risk factors and clinical outcomes of acute myeloid leukaemia with central nervous system involvement in adults
por: Cheng, Chieh-Lung, et al.
Publicado: (2015)

Diagnosis and Treatment of Patients With Acute Myeloid Leukemia With Myelodysplasia-Related Changes (AML-MRC)
por: Arber, Daniel A, et al.
Publicado: (2020)

Higher Decorin Levels in Bone Marrow Plasma Are Associated with Superior Treatment Response to Novel Agent-Based Induction in Patients with Newly Diagnosed Myeloma - A Retrospective Study
por: Huang, Shang-Yi, et al.
Publicado: (2015)

Functional association of NR4A3 downregulation with impaired differentiation in myeloid leukemogenesis
por: Lin, Shih-Chiang, et al.
Publicado: (2022)

Combined healthy lifestyle factors are more beneficial in reducing cardiovascular disease in younger adults: a meta-analysis of prospective cohort studies
por: Tsai, Ming-Chieh, et al.
Publicado: (2020)

Isochromosome 7p, i(7)(p10): A rare AML, myelodysplasia-related entity
por: Nejati, Reza, et al.
Publicado: (2023)

A CIBERSORTx-based immune cell scoring system could independently predict the prognosis of patients with myelodysplastic syndromes
por: Wang, Yu-Hung, et al.
Publicado: (2021)

Frequency of infusion-related reactions with CPX-351 treatment in an observational study in adults with newly diagnosed therapy-related AML or AML with myelodysplasia-related changes (AML-MRC)
por: Jacoby, Meagan A., et al.
Publicado: (2021)

Clinical and Microbiological Characteristics of Perianal Infections in Adult Patients with Acute Leukemia
por: Chen, Chien-Yuan, et al.
Publicado: (2013)

8-Hydroxydaidzein Induces Apoptosis and Inhibits AML-Associated Gene Expression in U-937 Cells: Potential Phytochemical for AML Treatment
por: Wu, Pei-Shan, et al.
Publicado: (2023)

Areca nut is associated with younger age of diagnosis, poor chemoradiotherapy response, and shorter overall survival in esophageal squamous cell carcinoma
por: Chen, Chang-Han, et al.
Publicado: (2017)

Author Correction: Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders
por: Tai, Chun-Hwei, et al.
Publicado: (2020)

Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders
por: Tai, Chun-Hwei, et al.
Publicado: (2020)

The distinct biological implications of Asxl1 mutation and its roles in leukemogenesis revealed by a knock-in mouse model
por: Hsu, Yueh-Chwen, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jbgc59gk95rs97jngq29c9vavd