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Systemic TM4SF5 overexpression in Apc(Min/+) mice promotes hepatic portal hypertension associated with fibrosis

Mutation of the gene for adenomatous polyposis coli (APC), as seen in Apc(Min/+) mice, leads to intestinal adenomas and carcinomas via stabilization of β-catenin. Transmembrane 4 L six family member 5 (TM4SF5) is involved in the development of non-alcoholic fatty liver disease, fibrosis, and cancer....

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Detalles Bibliográficos
Autores principales:	Lee, Joohyeong, Kim, Eunmi, Kang, Min-Kyung, Ryu, Jihye, Kim, Ji Eon, Shin, Eun-Ae, Pinanga, Yangie, Pyo, Kyung-hee, Lee, Haesong, Lee, Eun Hae, Cho, Heejin, Cheon, Jayeon, Kim, Wonsik, Jho, Eek-Hoon, Kim, Semi, Lee, Jung Weon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813423/ https://www.ncbi.nlm.nih.gov/pubmed/36104259 http://dx.doi.org/10.5483/BMBRep.2022.55.12.104

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