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The role of EZH1 and EZH2 in development and cancer

Polycomb Repressive Complex 2 (PRC2) exhibits key roles in mammalian development through its temporospatial repression of gene expression. EZH1 or EZH2 is the catalytic subunit of PRC2 that mediates the mono-, di- and tri-methylation of histone H3 lysine 27 (H3K27me1/2/3), H3K27me2/me3 being a hallm...

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Detalles Bibliográficos
Autores principales: Lee, Soo Hyun, Li, Yingying, Kim, Hanbyeol, Eum, Seounghyun, Park, Kyumin, Lee, Chul-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813427/
https://www.ncbi.nlm.nih.gov/pubmed/36476271
http://dx.doi.org/10.5483/BMBRep.2022.55.12.174

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