Preclinical evaluation of molecularly targeted fluorescent probes in perfused amputated human limbs

SIGNIFICANCE: This first-in-kind, perfused, and amputated human limb model allows for the collection of human data in preclinical selection of lead fluorescent agents. The model facilitates more accurate selection and testing of fluorophores with human-specific physiology, such as differential uptak...

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Detalles Bibliográficos
Autores principales: Bateman, Logan M., Hebert, Kendra A., Nunziata, Jenna A., Streeter, Samuel S., Barth, Connor W., Wang, Lei G., Gibbs, Summer L., Henderson, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2023
Materias:
Special Section on Seeing Inside Tissue with Optical Molecular Probes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813435/
https://www.ncbi.nlm.nih.gov/pubmed/36619496
http://dx.doi.org/10.1117/1.JBO.28.8.082802

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