Improving NK cell function in multiple myeloma with NKTR-255, a novel polymer-conjugated human IL-15

Multiple myeloma (MM) is characterized by an immunosuppressive microenvironment that enables tumor development. One of the mechanisms of immune evasion used by MM cells is the inhibition of natural killer (NK) cell effector functions; thus, the restoration of NK cell antitumor activity represents a...

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Detalles Bibliográficos
Autores principales: Fernandez, Rafael Alonso, Mayoral, Jessica Encinas, Pierre-Louis, Laetitia, Yao, Yao, Xu, Yan, Mu, Shidai, Martinez-Lopez, Joaquin, Primo, Daniel, Miyazaki, Takahiro, Prabhala, Rao, Anderson, Kenneth C., Overwijk, Willem W., Munshi, Nikhil C., Fulciniti, Mariateresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813531/
https://www.ncbi.nlm.nih.gov/pubmed/35882498
http://dx.doi.org/10.1182/bloodadvances.2022007985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813531/
https://www.ncbi.nlm.nih.gov/pubmed/35882498
http://dx.doi.org/10.1182/bloodadvances.2022007985

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