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Synergistic effect of doxorubicin lauroyl hydrazone derivative delivered by α-tocopherol succinate micelles for the treatment of glioblastoma

We hypothesized that tocopherol succinate (TOS) and D-α-tocopherol polyethylene2000 succinate (TPGS(2000)) micelles could work as a drug delivery system while enhancing the anti-cancer efficacy of doxorubicin lauryl hydrazone derivative (DOXC(12)) for the treatment of glioblastoma. The DOXC(12)-TOS-...

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Detalles Bibliográficos
Autores principales: Wang, Mingchao, Malfanti, Alessio, Bastiancich, Chiara, Préat, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813532/
https://www.ncbi.nlm.nih.gov/pubmed/36620521
http://dx.doi.org/10.1016/j.ijpx.2022.100147

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