G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region

Biological pacemakers, made of pacemaker-like cells, are promising in the treatment of bradyarrhythmia; however, the inefficiency of stem cell differentiation into pacemaker-like cells has limited their clinical application. Previous studies have reported that histone H3 at lysine 9 (H3K9) methylati...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Pei, Jin, Kai, Zhou, Jing, Gu, Jiangun, Gu, Xiang, Dong, Lijuan, Sun, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813554/
https://www.ncbi.nlm.nih.gov/pubmed/36484369
http://dx.doi.org/10.3892/mmr.2022.12908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813554/
https://www.ncbi.nlm.nih.gov/pubmed/36484369
http://dx.doi.org/10.3892/mmr.2022.12908

Ejemplares similares