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G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region

Biological pacemakers, made of pacemaker-like cells, are promising in the treatment of bradyarrhythmia; however, the inefficiency of stem cell differentiation into pacemaker-like cells has limited their clinical application. Previous studies have reported that histone H3 at lysine 9 (H3K9) methylati...

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Detalles Bibliográficos
Autores principales:	Xu, Pei, Jin, Kai, Zhou, Jing, Gu, Jiangun, Gu, Xiang, Dong, Lijuan, Sun, Xiaolin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813554/ https://www.ncbi.nlm.nih.gov/pubmed/36484369 http://dx.doi.org/10.3892/mmr.2022.12908

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