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Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study

INTRODUCTION: In China, salt intake is among the highest in the world (~11 g/day) and cardiovascular disease (CVD) accounts for 40% of deaths. We estimated the potential impact of reducing salt intake on CVD events in China, via systolic blood pressure (SBP). METHODS: To develop our model, we extrac...

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Autores principales: Tan, Monique, He, Feng, Morris, Joan K, MacGregor, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813635/
https://www.ncbi.nlm.nih.gov/pubmed/36619331
http://dx.doi.org/10.1136/bmjnph-2021-000408
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author Tan, Monique
He, Feng
Morris, Joan K
MacGregor, Graham
author_facet Tan, Monique
He, Feng
Morris, Joan K
MacGregor, Graham
author_sort Tan, Monique
collection PubMed
description INTRODUCTION: In China, salt intake is among the highest in the world (~11 g/day) and cardiovascular disease (CVD) accounts for 40% of deaths. We estimated the potential impact of reducing salt intake on CVD events in China, via systolic blood pressure (SBP). METHODS: To develop our model, we extracted the effect of salt reduction on SBP from a meta-regression of randomised trials and a population study, and that of SBP on CVD risk from pooled cohort studies. RESULTS: Reducing population salt intake in China by 1 g/day could lower the risk for ischaemic heart disease by about 4% (95% uncertainty interval 1.8%–7.7%) and the risk for stroke by about 6% (2.4%–9.3%). Should this reduced salt level be sustained until 2030,~9 million (M) (7M–10.8M) CVD events could be prevented, of which ~4M (3.1M–4.9M) would have been fatal. Greater and gradual salt intake reductions, to achieve WHO’s target of 30% reduction by 2025 or the Chinese government’s target of ≤5 g/day by 2030, could prevent ~1.5 or 2 times more CVD events and deaths, respectively. Should the prolonged effect of salt reduction over several years be accounted for, all estimates of CVD events and deaths prevented would be 25% greater on average. CONCLUSION: Bringing down the high salt intake levels in China could result in large reductions in CVD. An easily achievable reduction of 1 g/day could prevent ~9M CVD events by 2030. Urgent action must be taken to reduce salt intake in China.
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spelling pubmed-98136352023-01-06 Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study Tan, Monique He, Feng Morris, Joan K MacGregor, Graham BMJ Nutr Prev Health Original Research INTRODUCTION: In China, salt intake is among the highest in the world (~11 g/day) and cardiovascular disease (CVD) accounts for 40% of deaths. We estimated the potential impact of reducing salt intake on CVD events in China, via systolic blood pressure (SBP). METHODS: To develop our model, we extracted the effect of salt reduction on SBP from a meta-regression of randomised trials and a population study, and that of SBP on CVD risk from pooled cohort studies. RESULTS: Reducing population salt intake in China by 1 g/day could lower the risk for ischaemic heart disease by about 4% (95% uncertainty interval 1.8%–7.7%) and the risk for stroke by about 6% (2.4%–9.3%). Should this reduced salt level be sustained until 2030,~9 million (M) (7M–10.8M) CVD events could be prevented, of which ~4M (3.1M–4.9M) would have been fatal. Greater and gradual salt intake reductions, to achieve WHO’s target of 30% reduction by 2025 or the Chinese government’s target of ≤5 g/day by 2030, could prevent ~1.5 or 2 times more CVD events and deaths, respectively. Should the prolonged effect of salt reduction over several years be accounted for, all estimates of CVD events and deaths prevented would be 25% greater on average. CONCLUSION: Bringing down the high salt intake levels in China could result in large reductions in CVD. An easily achievable reduction of 1 g/day could prevent ~9M CVD events by 2030. Urgent action must be taken to reduce salt intake in China. BMJ Publishing Group 2022-08-16 /pmc/articles/PMC9813635/ /pubmed/36619331 http://dx.doi.org/10.1136/bmjnph-2021-000408 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Research
Tan, Monique
He, Feng
Morris, Joan K
MacGregor, Graham
Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study
title Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study
title_full Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study
title_fullStr Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study
title_full_unstemmed Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study
title_short Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study
title_sort reducing daily salt intake in china by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813635/
https://www.ncbi.nlm.nih.gov/pubmed/36619331
http://dx.doi.org/10.1136/bmjnph-2021-000408
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