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Inferring direction of associations between histone modifications using a neural processes-based framework
Current technologies do not allow predicting interactions between histone post-translational modifications (HPTMs) at a system-level. We describe a computational framework, imputation-followed-by-inference, to predict directed association between two HPTMs using EpiTOF, a mass cytometry-based platfo...
Autores principales: | Ganesan, Ananthakrishnan, Dermadi, Denis, Kalesinskas, Laurynas, Donato, Michele, Sowers, Rosalie, Utz, Paul J., Khatri, Purvesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813700/ https://www.ncbi.nlm.nih.gov/pubmed/36619977 http://dx.doi.org/10.1016/j.isci.2022.105756 |
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