Cargando…

Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress

The potential coexistence of Alzheimer's disease (AD) and atrial fibrillation (AF) is increasingly common as aging-related diseases. However, little is known about mechanisms responsible for atrial remodeling in AD pathogenesis. α7 nicotinic acetylcholine receptors (α7nAChR) has been shown to h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Jikai, Yu, Liming, Xue, Xiaodong, Xu, Yinli, Huang, Tao, Xu, Dengyue, Wang, Zhishang, Luo, Linyu, Wang, Huishan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813735/ https://www.ncbi.nlm.nih.gov/pubmed/36603528 http://dx.doi.org/10.1016/j.redox.2022.102594

Ejemplares similares

Activation of cannabinoid receptor 2 attenuates Angiotensin II-induced atrial fibrillation via a potential NOX/CaMKII mechanism
por: Xu, Dengyue, et al.
Publicado: (2022)

Sulfonium Ligands of the α7 nAChR
por: Horenstein, Nicole A., et al.
Publicado: (2021)

Regulation of the acetylcholine/α7nAChR anti-inflammatory pathway in COVID-19 patients
por: Courties, Alice, et al.
Publicado: (2021)

Vagal α7nAChR signaling regulates α7nAChR(+)Sca1(+) cells during lung injury repair
por: Chen, Xiaoyan, et al.
Publicado: (2020)

Farnesyl Transferase Inhibitor Lonafarnib Enhances α7nAChR Expression Through Inhibiting DNA Methylation of CHRNA7 and Increases α7nAChR Membrane Trafficking
por: Chen, Tingting, et al.
Publicado: (2020)

Activation of α7 nAChR by PNU-282987 improves synaptic and cognitive functions through restoring the expression of synaptic-associated proteins and the CaM-CaMKII-CREB signaling pathway
por: Wang, Xiao-Ling, et al.
Publicado: (2020)

α-Conotoxin as Potential to α7-nAChR Recombinant Expressed in Escherichia coli
por: Liu, Yanli, et al.
Publicado: (2020)

Unique Pharmacological Properties of α-Conotoxin OmIA at α7 nAChRs
por: Ho, Thao N.T., et al.
Publicado: (2021)

New Insights on Neuronal Nicotinic Acetylcholine Receptors as Targets for Pain and Inflammation: A Focus on α7 nAChRs
por: Bagdas, Deniz, et al.
Publicado: (2018)

Development of (11)C-Labeled ASEM Analogues for the Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR)
por: Nag, Sangram, et al.
Publicado: (2022)

Discoveries and future significance of research into amyloid-beta/α7-containing nicotinic acetylcholine receptor (nAChR) interactions()
por: Whiteaker, Paul, et al.
Publicado: (2023)

Interacting with α7 nAChR is a new mechanism for AChE to enhance the inflammatory response in macrophages
por: Liu, Etta Y.L., et al.
Publicado: (2020)

The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis
por: Hu, Song, et al.
Publicado: (2021)

Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization
por: Bondarenko, Vasyl, et al.
Publicado: (2023)

Correction to “Development of (11)C-Labeled ASEM Analogues for Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR)”
por: Nag, Sangram, et al.
Publicado: (2022)

E-cigarette-Induced Pulmonary Inflammation and Dysregulated Repair are Mediated by nAChR α7 Receptor: Role of nAChR α7 in ACE2 Covid-19 receptor regulation
por: Wang, Qixin, et al.
Publicado: (2020)

Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis
por: Liu, Yuan, et al.
Publicado: (2021)

α7nAchR/NMDAR coupling affects NMDAR function and object recognition
por: Li, Shupeng, et al.
Publicado: (2013)

In silico studies of ASEM analogues targeting α7-nAChR and experimental verification
por: Zhou, Yang, et al.
Publicado: (2021)

Simvastatin Enhances Activity and Trafficking of α7 Nicotinic Acetylcholine Receptor in Hippocampal Neurons Through PKC and CaMKII Signaling Pathways
por: Chen, Tingting, et al.
Publicado: (2018)

The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site
por: Gulsevin, Alican, et al.
Publicado: (2021)

Neuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor (α7nAchR)-mediated autophagy flux
por: Jeong, Jae-Kyo, et al.
Publicado: (2015)

RNA sequencing data describing transcriptional changes in aorta of ApoE-/- mice after alpha 7 nicotinic acetylcholine receptor (α7nAChR) stimulation
por: Ulleryd, Marcus A., et al.
Publicado: (2020)

Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders
por: Kalkman, Hans O., et al.
Publicado: (2016)

APS8, a Polymeric Alkylpyridinium Salt Blocks α7 nAChR and Induces Apoptosis in Non-Small Cell Lung Carcinoma
por: Zovko, Ana, et al.
Publicado: (2013)

E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation
por: Wang, Qixin, et al.
Publicado: (2020)

Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs
por: Lin, Bo, et al.
Publicado: (2016)

Semisynthetic Analogues of Toxiferine I and Their Pharmacological Properties at α7 nAChRs, Muscle-Type nAChRs, and the Allosteric Binding Site of Muscarinic M(2) Receptors
por: Zlotos, Darius P., et al.
Publicado: (2014)

Blockade of Neuronal α7-nAChR by α-Conotoxin ImI Explained by Computational Scanning and Energy Calculations
por: Yu, Rilei, et al.
Publicado: (2011)

Activation of α7-nAChRs Promotes the Clearance of α-Synuclein and Protects Against Apoptotic Cell Death Induced by Exogenous α-Synuclein Fibrils
por: Zhao, Jifeng, et al.
Publicado: (2021)

In Vivo Amphetamine Action is Contingent on αCaMKII
por: Steinkellner, Thomas, et al.
Publicado: (2014)

Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?
por: Mohammadi, Sarasa A., et al.
Publicado: (2015)

The current agonists and positive allosteric modulators of α7 nAChR for CNS indications in clinical trials
por: Yang, Taoyi, et al.
Publicado: (2017)

Role of α7nAChR-NMDAR in sevoflurane-induced memory deficits in the developing rat hippocampus
por: Tang, XiaoHong, et al.
Publicado: (2018)

Activation of α7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson’s Disease Rats
por: Zhou, Li, et al.
Publicado: (2021)

Total synthesis of the natural (−)-205B alkaloid and its activity toward α7 nAChRs
por: Mazeh, Sara, et al.
Publicado: (2022)

Escherichia Coli -induced Inflammation Changes the Expression of Acetylcholine Receptors (M2R, M3R, and α-7 nAChR) in the Pig Uterus
por: Jana, Barbara, et al.
Publicado: (2020)

Calcium imaging with genetically encoded sensor Case12: Facile analysis of α7/α9 nAChR mutants
por: Shelukhina, Irina, et al.
Publicado: (2017)

Short-Term High-Fat Diet Consumption Reduces Hypothalamic Expression of the Nicotinic Acetylcholine Receptor α7 Subunit (α7nAChR) and Affects the Anti-inflammatory Response in a Mouse Model of Sepsis
por: Souza, Anelise Cristina Parras, et al.
Publicado: (2019)

TTF-1 regulates α(5 )nicotinic acetylcholine receptor (nAChR) subunits in proximal and distal lung epithelium
por: Reynolds, Paul R, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_b2kcch75hkd00bcngj8u1jpnj2